Uncovering a way for pro-B cells to change trajectory microbiologystudy
Development of B cells, white blood cells that make antibodies, follows a progression of stages: common lymphoid progenitors, pre-pro-B cells, […]
Genetics
Using zebrafish as a model to study the underlying mechanism of Nager syndrome microbiologystudy
Given that the developmental processes of zebrafish facial structure is similar to human, they can be leveraged as a low-cost
Gene editing approach helps launch first-in-human clinical trial for rare genetic disease microbiologystudy
Credit: Unsplash/CC0 Public Domain A collaborative effort between investigators at the National Institutes of Health’s National Institute of Allergy and
Uncovering a way for pro-B cells to change trajectory microbiologystudy
Credit: Pixabay/CC0 Public Domain Development of B cells, white blood cells that make antibodies, follows a progression of stages: common
Genetics
High-potency cannabis use is tied to epigenetic changes, study suggests microbiologystudy
Credit: Unsplash/CC0 Public Domain A study published in Molecular Psychiatry is the first to suggest that the use of high-potency
‘Pincer attack’ on transcription factors offers new possibilities for future blood cancer therapies microbiologystudy
Correlation and ChIP-seq analyses indicate the existence of non-overlapping MYC- and JUNB-transcriptional programs in MM cells. Credit: Blood Cancer Journal
Scientists use CRISPR tools to safely disable gene mutation linked to treatment-resistant melanoma microbiologystudy
Credit: Pixabay/CC0 Public Domain In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR
New study offers revolutionary method for analyzing cell interactions in cancer microbiologystudy
DIISCO’s input is cell-type proportions over time and gene expression of known receptor-ligand pairs. Its output is cell-type dynamics over
Using genes to predict whether a different diet helps irritable bowel syndrome microbiologystudy
Credit: Clinical Gastroenterology and Hepatology (2024). DOI: 10.1016/j.cgh.2024.09.004 Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal pain,
New research confirms location of pseudoautosomal region boundary between the two sex chromosomes microbiologystudy
Graphical abstract. Credit: The American Journal of Human Genetics (2024). DOI: 10.1016/j.ajhg.2024.09.005 In the 1980s, scientists knew little about the