Uncovering a way for pro-B cells to change trajectory microbiologystudy
Credit: Pixabay/CC0 Public Domain Development of B cells, white blood cells that make antibodies, follows a progression of stages: common […]
Genetics
Genetics
High-potency cannabis use is tied to epigenetic changes, study suggests microbiologystudy
Credit: Unsplash/CC0 Public Domain A study published in Molecular Psychiatry is the first to suggest that the use of high-potency
‘Pincer attack’ on transcription factors offers new possibilities for future blood cancer therapies microbiologystudy
Correlation and ChIP-seq analyses indicate the existence of non-overlapping MYC- and JUNB-transcriptional programs in MM cells. Credit: Blood Cancer Journal
Scientists use CRISPR tools to safely disable gene mutation linked to treatment-resistant melanoma microbiologystudy
Credit: Pixabay/CC0 Public Domain In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR
New study offers revolutionary method for analyzing cell interactions in cancer microbiologystudy
DIISCO’s input is cell-type proportions over time and gene expression of known receptor-ligand pairs. Its output is cell-type dynamics over
Using genes to predict whether a different diet helps irritable bowel syndrome microbiologystudy
Credit: Clinical Gastroenterology and Hepatology (2024). DOI: 10.1016/j.cgh.2024.09.004 Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal pain,
New research confirms location of pseudoautosomal region boundary between the two sex chromosomes microbiologystudy
Graphical abstract. Credit: The American Journal of Human Genetics (2024). DOI: 10.1016/j.ajhg.2024.09.005 In the 1980s, scientists knew little about the
Study finds genetics, not lifestyle, is a major cause of gout microbiologystudy
Linking of insulin signaling, the tricarboxylic acid cycle and epigenomic reprogramming cellular pathways with candidate gout-associated genes. Credit: Nature Genetics
Extrachromosomal DNA could be a target of future cancer therapies microbiologystudy
Longitudinal amplicon analysis. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01949-7 Research published in Nature Genetics on Oct.14, by Yale Cancer Center
Genetics
New study reveals promising therapy that blocks microRNAs to treat myotonic dystrophy type 1 microbiologystudy
Integrated evaluation of the antimiR’s therapeutic potential. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adn6525 A team of researchers has identified a