An integral T cell pathway has implications for understanding sex-based immune response microbiologystudy
T cells from a healthy human female donor were stimulated with antibodies anti-CD3 and anti-CD28 for 48 hours. On the […]
Genetics
Genetics
Genetic analysis of 25,000 Chinese mothers and infants reveals unique genes associated with disease risk microbiologystudy
Credit: Unsplash/CC0 Public Domain Genome-wide association studies have great potential for advancing our understanding of the genetic background of diseases,
Scientists create first map of DNA modification in the developing human brain microbiologystudy
Fluorescent image of a developing human hippocampus. Credit: Oier Pastor-Alonso/UCSF A UCLA-led study has provided an unprecedented look at how
Newly discovered genetic marker could pave the way for future Alzheimer’s disease therapeutics microbiologystudy
While previous studies have made strides in identifying genetic variants associated with amyloid deposition, understanding the genetic drivers of tau
DOCK8 mutation disrupts helper T cell differentiation via glycolytic pathway regulation microbiologystudy
DOCK8 mutation increases serum IgE levels and decreases dedicator of cytokinesis 8 (DOCK8) protein in T cells. Credit: MedComm (2024).
The secret to slimming? Special ‘skinny genes’ double weight loss microbiologystudy
A depiction of the interaction between alleles and body mass over both intervention groups separately (panel A) and a moderator
Genetics
Novel gene therapy shows promise in targeting a mutation linked to epilepsy microbiologystudy
Clearance of mutant protein & restoration of normal neuronal activity by Gapmer ASO. Credit: NUS Medicine Researchers from the Yong
Study uncovers mutations and DNA structures driving bladder cancer microbiologystudy
Timing mutagenic processes in UC evolution. Credit: Nature (2024). DOI: 10.1038/s41586-024-07955-3 How bladder cancer originates and progresses has been illuminated
Genetics
Study finds new genetic loci associated with dementia microbiologystudy
Manhattan plots identify loci associated with each of the 11 NPEs included in this study. Credit: Nature Genetics (2024). DOI:
New technique that makes competition between tumor cells visible can help personalize treatments for multiple myeloma microbiologystudy
A clonal competition assay showing populations of cells with different mutations. Depending on the mutation, each population of cells is