Brain organoid model implicates gene in disease progression microbiologystudy
Huntington’s Disease organoids (right) exhibit almost no neural progenitors (red) and also show defects in cellular polarity (yelllow). These defects […]
Genetics
Genetics
Finding new treatments for genetic tumor-predisposition syndrome microbiologystudy
Clinically diverse cNFs give rise to organoids with similar histopathological features. Credit: Cell Reports Methods (2024). DOI: 10.1016/j.crmeth.2024.100772 A new report
Genetics
Reading your biological age in your blood or saliva? It’s not as simple as that, study shows microbiologystudy
Epigenetic clocks are impacted by the differentiation stage and proliferation history of cells, as well as by age-associated changes in
Two proteins identified as potential targets to improve ALS symptoms microbiologystudy
Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114626 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is incurable. The disease is
Detective algorithm predicts best drugs for genetic disorders and cancer microbiologystudy
Ben Lehner (left) and Fran Supek (right), the co-corresponding authors of the research. Credit: Centre for Genomic Regulation A computational
Gut molecule slows fat burning during fasting
In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the
Targetable variant RAD51D found in Chinese patients microbiologystudy
Spectrum of germline variants in our cohort and statistics on variant classification and pathogenicity categories. BRCA1, BRCA2, and RAD51D are
Benefits and downside of fasting
Low-calorie diets and intermittent fasting have been shown to have numerous health benefits: They can delay the onset of some
Self-repairing mitochondria use novel recycling system microbiologystudy
Mitochondria, the so-called “powerhouse of the cell,” depend on a newly discovered recycling mechanism identified by scientists at The Hospital
Researchers uncover the secrets of ‘plant puberty’
Researchers have identified the genetic changes linked to why plants go through a developmental change similar to “puberty” at different