Researchers discover a genetic disposition increasing the risk of breast cancer metastasis microbiologystudy
When mice are engineered to carry a variant of the human PCSK9 gene, they experience higher rates of breast cancer […]
Genetics
Genetics
Scientists identify a probable contributor to weakness of the aorta in people with genetic disorder microbiologystudy
Downregulation of transcripts associated with ECM–receptor interactions and upregulation of stress and inflammation pathways in Tgfbr1M318R/+ LDS VSMCs. Credit: Nature
Genetics
Genetic code discovery could redefine understanding of cancer origins microbiologystudy
Tumor cells synthesize and export Tu-Stroma to stromal cells via DDX3X-assisted exosomal packaging. Credit: Nature Biotechnology (2024). DOI: 10.1038/s41587-024-02453-3 A
Genetics
Targeting novel molecular mechanisms may repair damaged DNA in cancer cells microbiologystudy
EZH2 directly interacts with PARP1 and represses PARP1 catalytic activity. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adl2804 Northwestern Medicine investigators have
Genetics
New method enables protein analysis accounting for population diversity microbiologystudy
Impact of genetic variation in the populations of the 1000 Genomes Project on the proteomic search space. Credit: Nature Methods
African men most at risk of prostate cancer—new study flags genetic causes microbiologystudy
Credit: Unsplash/CC0 Public Domain A breakthrough study has identified the genetic risk factors that contribute to increased prostate cancer in
Genetics
Some people say they have a high pain threshold. Here’s why microbiologystudy
Credit: Mikhail Nilov from Pexels We’ve all heard someone claim they have a “high pain threshold” as if it’s a
Single mutation in H5N1 influenza surface protein could enable easier human infection microbiologystudy
A single modification in the protein found on the surface of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus
New model for replication of BKPyV virus, a major cause of kidney transplant failure microbiologystudy
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.