Hundreds of new cancer driver genes predicted by algorithm microbiologystudy
Applying models of splicing dependency to samples from cancer patients to prioritize splicing vulnerabilities with therapeutic potential. Credit: Nature Communications […]
Genetics
Study explores the cell-type-specific effects of aging and sex on human cortical neurons microbiologystudy
(A) Study design. (B) UMAP embedding of nuclei assigned to 11 excitatory, 10 inhibitory, and 3 glial types using DNA
Gene found in ovarian cancer cells identified as potential new target for treatment microbiologystudy
A potential model for ZIC2 functions in EOC. Credit: Oncogene (2024). DOI: 10.1038/s41388-024-03026-z A University of Alberta research team has
Risk gene for bipolar disorder decoded microbiologystudy
Consequences of Val147Leu substitution on ADCY2 activity and subcellular localization. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02663-w The risk gene adenylyl
Genetics
Researchers pinpoint key gene mutations, new mechanisms that cause brain bleeding and dementia microbiologystudy
Mechanisms of COL4A1/COL4A2 variants in CSVD. Credit: eBioMedicine (2024). DOI: 10.1016/j.ebiom.2024.105315 Scientists have revealed new insights into the mechanisms behind
Rare genetic variants linked to bicuspid aortic valve disease in young adults identified microbiologystudy
Credit: CC0 Public Domain Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults
Long noncoding RNAs emerge as promising biomarkers for mood disorders microbiologystudy
The network plot illustrates the interconnectedness of three distinct mood disorders (major depressive disorder: MDD, bipolar disorder: BD, and suicidal
New technique allows comprehensive genetic examination of embryos with a single test microbiologystudy
Credit: Pixabay/CC0 Public Domain Researchers from Karolinska Institutet and Maastricht University have developed a technique that enables the examination of
Genomic dark matter solves butterfly evolutionary riddle microbiologystudy
A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly