Thiopurine metabolism and thiopurine methyl transferase (TPMT) enzyme activity assay. Azathioprine (AZA) is converted into 6-mercaptopurine (6-MP), which can also […]
Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-54089-1 New potential therapeutic targets have been identified for diabetic kidney disease (DKD)—the leading cause
Credit: Unsplash/CC0 Public Domain Smokers with myelodysplastic syndromes (MDS) or a precursor condition had elevated levels of genetic mutations linked
A research team led by Prof. Julia Esser-von Bieren from the Center of Allergy and Environment (ZAUM) at Helmholtz Munich
Credit: Unsplash/CC0 Public Domain A new study demonstrates how universal genetic testing for breast cancer can ensure no patient is
Genotype–phenotype associations. 31 SNPs for which at least one nominal association with a neuropathological phenotype was discovered, are shown on
When mice are engineered to carry a variant of the human PCSK9 gene, they experience higher rates of breast cancer
Downregulation of transcripts associated with ECM–receptor interactions and upregulation of stress and inflammation pathways in Tgfbr1M318R/+ LDS VSMCs. Credit: Nature
Tumor cells synthesize and export Tu-Stroma to stromal cells via DDX3X-assisted exosomal packaging. Credit: Nature Biotechnology (2024). DOI: 10.1038/s41587-024-02453-3 A