Immune system review provides insight into more effective biotechnology microbiologystudy
Macrophage cells are the immune system’s frontline soldiers, early on the scene to protect the body from foreign invaders. These […]
Genetics
Genome sequencing and AI analysis reveal hidden genetic markers of breast cancer microbiologystudy
Variant analysis pipeline. (A) Preprocessing flow. (B) ML scoring EVE (EVEmodel), ESM (ESM-1v), FIRM (functional impact rating at the molecular
Researchers discover underlying mechanisms that make CRISPR an effective gene editing tool microbiologystudy
CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy.
A potential advance against RAS-driven cancers—researchers find certain inhibitors can short-circuit mutation signals microbiologystudy
Credit: Nature (2024). DOI: 10.1038/s41586-024-08283-2 Each year, more than 3 million people are diagnosed with cancers driven by mutations in
New pathway for sensing cold temperatures identified in rice
A gene called COLD6 contributes to cold tolerance in rice, potentially offering a pathway to use molecular design to breed
Researchers create large genomic database of Latin American populations to tackle health disparities microbiologystudy
DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH It is commonly known that
New method to analyze complex genetic data could be the key to tackling rare diseases microbiologystudy
Credit: CC0 Public Domain Scientists from the University of Nottingham have developed a new method of genetic analysis, which extracts
Genetics
Researchers map communities of single cells in metastatic breast cancers microbiologystudy
Profiling of MBC biopsies using scRNA-seq, snRNA-seq and four spatial expression methods. Credit: Nature Medicine (2024). DOI:10.1038/s41591-024-03215-z A single biopsy
Study shows need for routine screening in clinical settings microbiologystudy
Case Proportions for Each Mental Health Diagnosis, Across Polygenic Score (PGS) Deciles and Stratified by Sexual Trauma (ST) History. Credit:
Key mechanism in human lung development identified microbiologystudy
Immunofluorescence detection of IGFBP3 in human lung embryonic and fetal tissues. Credit: Stem Cell Research & Therapy (2024). DOI: 10.1186/s13287-024-03883-1