Cracking the code of DNA circles in cancer: Scientists uncover potential therapy microbiologystudy
On the left, ecDNAs that link together to enhance cancer cell growth tend to be inherited together by daughter cells […]
Genetics
Stem cells can tailor their role in gene therapy based on the underlying disease, study suggests microbiologystudy
Credit: CC0 Public Domain RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt
Testing thousands of RNA enzymes helps find first ‘twister ribozyme’ in mammals microbiologystudy
The “RNA world” hypothesis proposes that the earliest life on Earth may have been based on RNA — a single-stranded
Innate immune defense system plays an unexpected role in maintaining genome stability, researchers find microbiologystudy
Credit: Pixabay/CC0 Public Domain Along with defending against pathogens, the body’s innate immune system helps to protect the stability of
Scientists develop test to better track whooping cough strains amid outbreak in Australia microbiologystudy
Credit: Pixabay/CC0 Public Domain Researchers at UNSW Sydney and the University of Technology Sydney (UTS) have developed a new genomic
Scientists identify 16 genes that aid cancer cell survival in low-oxygen regions microbiologystudy
GFP+ CTCs retain hypoxia and NF-kB signaling. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51995-2 Scientists at the Johns Hopkins Kimmel Cancer
Genetics
Two genes linked to rheumatoid arthritis and osteoporosis could serve as targets for diagnosis and treatment microbiologystudy
Of the many genes involved in rheumatoid arthritis and osteoporosis, the researchers identified two key genes, ATXN2L and MMP14, that
Long-read sequencing technique helps analyze chromosomal abnormalities in complex health conditions microbiologystudy
Subway plots of two complex rearrangements: (A) a complex dup-trip-quad-trip-dup-del on Chromosome 2 observed in P4 and (B) a clustered
Genetics
Study identifies key cell subpopulation and associated gene signature in neuroblastoma microbiologystudy
Credit: Frontiers of Medicine (2024). DOI: 10.1007/s11684-024-1081-7 Neuroblastoma (NB), the most prevalent extracranial solid tumor in children, poses a significant