Scientists successfully reverse liver fibrosis in mice microbiologystudy
Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis—a potentially lethal stiffening of tissue that, once begun, is irreversible. […]
Genetics
Researchers solve medical mystery of neurological symptoms in kids microbiologystudy
Researchers at WashU Medicine collaborated with an international team of doctors and scientists to identify the cause of a rare
Study identifies 51 amyotrophic lateral sclerosis-associated mutations that could help diagnose the disease microbiologystudy
Credit: Pixabay/CC0 Public Domain Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an
Genetics
In vivo and vitro experiments show that long noncoding RNA treatment alleviates pathological cardiac hypertrophy microbiologystudy
Credit: Frontiers of Medicine (2024). DOI: 10.1007/s11684-024-1065-7 In a recent study, the regulatory role of the long noncoding RNA (lncRNA)
Immune system review provides insight into more effective biotechnology microbiologystudy
Macrophage cells are the immune system’s frontline soldiers, early on the scene to protect the body from foreign invaders. These
Genome sequencing and AI analysis reveal hidden genetic markers of breast cancer microbiologystudy
Variant analysis pipeline. (A) Preprocessing flow. (B) ML scoring EVE (EVEmodel), ESM (ESM-1v), FIRM (functional impact rating at the molecular
Researchers discover underlying mechanisms that make CRISPR an effective gene editing tool microbiologystudy
CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy.
A potential advance against RAS-driven cancers—researchers find certain inhibitors can short-circuit mutation signals microbiologystudy
Credit: Nature (2024). DOI: 10.1038/s41586-024-08283-2 Each year, more than 3 million people are diagnosed with cancers driven by mutations in
New pathway for sensing cold temperatures identified in rice
A gene called COLD6 contributes to cold tolerance in rice, potentially offering a pathway to use molecular design to breed