Human pluripotent stem cell-derived models of the hippocampus microbiology

Abbreviations

hPSC

human pluripotent stem cells

CRISPR

clustered regularly interspaced short palindromic repeats

BMP

bone morphogenic protein

PROX1

prospero homeobox protein 1

GSK3

glycogen synthase kinase 3

LHX2

LIM-homeodomain protein

LEF1

lymphoid enhancer binding factor 1

HOPX

homeodomain-only protein homeobox

ZBTB20

zinc finger and BTB domain containing 20

MAP2

microtubule-associated protein 2

vGLUT

vesicular glutamate transporter

GFAP

glial fibrillary acidic protein

S100B

S100 calcium-binding protein B

GRIK1

glutamate ionotropic receptor kainate type subunit 1

SARS-CoV-2

severe acute respiratory syndrome coronavirus 2

iPSC

induced pluripotent stem cell

APP

amyloid-beta precursor protein

LC-MS/MS

liquid chromatography-tandem mass spectrometry

t-SNE

t-distributed stochastic neighbor embedding

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