Unveiling a novel signalling pathway involving NRF2 and PGAM5 in regulating the mitochondrial unfolded protein response in stressed cardiomyocytes microbiology

mitochondrial unfolded protein response

NFE2 like bZIP transcription factor 2

PGAM family member 5

kelch like ECH associated protein 1

adenosine triphosphate

Activating Transcription Factor 5

heat shock protein family E Hsp10 member 1

heat shock protein family D Hsp60 member 1

caseinolytic mitochondrial matrix peptidase proteolytic subunit

lon peptidase 1, mitochondrial

mitochondrial DnaJ heat shock protein family Hsp40 member A3

reactive oxygen species

outer mitochondrial membrane

Tetramethylrhodamine Ethyl Ester Perchlorate

polyADP-ribose polymerase

glutathione S-transferase alpha 2

glutamate-cysteine ligase, catalytic subunit

gamitrinib triphenylphosphonium

Isoprenaline hydrochloride

antioxidant responsive element

dynamin-related protein 1

traumatic brain injury

PTEN induced kinase 1

Parkin RBR E3 ubiquitin-protein ligase

FUN14 domain containing 1

multiplicity of infection

quantitative polymerase chain reaction

4′,6-diamidino-2-phenylindole

mitochondrial dynamics proteins of 49 and 51 kDa

standard error of the mean