The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while cows can walk mere minutes after birth and run not long after. University of California San Diego researchers, using powerful […]
Credit: CC0 Public Domain Diagnosing the genetic cause of a disease can aid in finding therapies and directing treatment, but often these diagnoses occur long after the disease has impacted a patient’s life. In a new study, researchers from Children’s Hospital of Philadelphia (CHOP) used machine learning and artificial intelligence to comb through medical records
(a) Human cortical ovarian tissues from BRCA1 (n = 8) and BRCA2 (n = 10) mutation carriers (mc) were immunohistochemically stained for DDX4 as a marker of oocytes. Photomicrographs are representative of the classifications used to identify i. primordial follicles; bar = 100 μm, ii. primary follicles; bar = 100 μm, iii. secondary follicles; bar = 100 μm iv-v. abnormal follicles; bar = 100 μm vi. abnormal follicles; bar = 200 μm. (b) Total
A research team led by University of Liège scientists has published a groundbreaking study on malignant catarrhal fever (MCF). This disease is caused by the alcelaphine gammaherpesvirus 1 (AlHV-1), which infects its natural host, the wildebeest. This study sheds light on the mechanisms by which this virus, which is asymptomatic and latent in the wildebeest,
Blood testing using technology called EpiSign. Credit: London Health Sciences Centre Researchers at London Health Sciences Centre (LHSC) and Lawson Health Research Institute are using advanced technology and artificial intelligence (AI) to diagnose rare diseases and prenatal exposure-related birth abnormalities in two studies published today, one study in American Journal of Human Genetics and the
UNSW Sydney researchers have made new discoveries of fundamental differences in biological processes between males and females — by interrogating the unique and diverse sex chromosome systems of the platypus and the chicken. The findings, published today in Proceedings of the National Academy of Sciences (PNAS), are a surprise in the field of genetics. The
Credit: Pixabay/CC0 Public Domain Research on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity and multifaceted nature of obesity perfectly resonating with more modern discoveries. Researchers at Pennington Biomedical have collected nearly a century’s worth of considerations and advancements to frame their perspectives on modern
Inactivation of a DNA repair gene called FANCM enhances the formation of DNA damage and chromosomal instability induced by a PARP inhibitor, leading to massive cancer cell death. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114464 A research team led by Professor Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong
Credit: The American Journal of Human Genetics (2024). DOI: 10.1016/j.ajhg.2024.06.018 A genetic diagnostic method using a small sample of skin from the upper arm could identify rare neurodevelopmental disorders in a non-invasive way, according to researchers at the University of Adelaide. Currently, conditions caused by a significant disruption during brain development, like Rett Syndrome, epilepsy
Credit: CC0 Public Domain Though it is exceedingly rare, some people diagnosed with amyotrophic lateral sclerosis (ALS) partially or fully recover from the lethal neurodegenerative disease. A better understanding of this baffling phenomenon, reported in medical literature for at least 60 years, could point to potential new treatment approaches. To that end, researchers at Duke