Genetics

Credit: Cancer Cell (2024). DOI: 10.1016/j.ccell.2024.06.006 A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin. The findings appear in Cancer Cell. Led by Arul Chinnaiyan, […]

Credit: Unsplash/CC0 Public Domain Investigators in the Parkinson’s Foundation-backed PD GENEration study—which reached its goal of 15,000 participants ahead of schedule this spring—found that 13% of participants have a genetic form of Parkinson’s disease (PD), which is a significant observation compared to long-standing estimates. Results from the first 3.5 years of the study, which examined

Credit: Pixabay/CC0 Public Domain We normally associate our age with the year we are born. However, what if your age could be better associated with other factors like health, diet, exercise, occupation and education level? A new study by the University of Hawaiʻi at Mānoa has discovered for the first time that Native Hawaiians experience

Cumulative incidence of heart failure stratified by transthyretin levels. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-50231-1 Physician–scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine have uncovered significant findings regarding the impact of transthyretin, or TTR, protein levels on heart disease risk. The study, recently published in Nature Communications, explores how

Credit: CC0 Public Domain About 37 million people in the United States have chronic kidney disease and studies show that genetics may explain between 10% and 20% of cases in adults (and as many as 70% of cases in children). But genetic testing in kidney disease is not very common compared to genetic testing in